Trial intelligence / Profile preview

Tadalafil with Chemoradiotherapy for IDH-wildtype Astrocytoma

NCT04757662Phase 1Completed

Sponsor
Washington University School of Medicine
Start
May 2021
Primary completion
Jun 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of tadalafil in astrocytoma and glioblastoma (GBM), sponsored by Washington University School of Medicine. Primary endpoints: Relative change of MDSCs in peripheral blood and Frequency of adverse events as measured by CTCAE v5.0. Started May 2021; status: completed.

02

Drugs

tadalafil
03

Conditions

astrocytomaglioblastoma (GBM)

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