Trial intelligence / Profile preview

TOTEM: Repotrectinib + Osimertinib in EGFR-mutant NSCLC

NCT04772235Phase 1Recruiting

Sponsor
Instituto Oncológico Dr. Rosell
Start
Feb 2022
Primary completion
Apr 2026
Modality
Fragment-Derived Small Molecules, Allosteric Modulators, Orthosteric Ligands
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of repotrectinib in non-small cell lung cancer (NSCLC), sponsored by Instituto Oncológico Dr. Rosell. Primary endpoints: Adverse Events at 48 months and Incidence of Dose Limiting Toxicities at 21 days. Started Feb 2022; status: recruiting.

02

Drugs

repotrectinib
03

Conditions

non-small cell lung cancer (NSCLC)

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