Trial intelligence / Profile preview

Evazarsen in Chronic Heart Failure With Reduced Ejection Fraction

NCT04836182Phase 2Completed

Sponsor
Ionis Pharmaceuticals
Start
Jun 2021
Primary completion
Oct 2022
Modality
Small Interfering RNA (siRNA), Modified DNA Oligonucleotides, Single-strand DNA
Countries
3
01

Overview

Phase 2, randomised, double-blind trial in heart failure with reduced ejection fraction (HFrEF) comparing Evazarsen with Placebo (2 arms). Primary endpoint: Percent Change in Plasma Angiotensinogen Concentration From Baseline to Study Day 85. Started Jun 2021; status: completed.

02

Drugs

evazarsen
03

Conditions

heart failure with reduced ejection fraction (HFrEF)

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