Trial intelligence / Profile preview

CHLOE pancreas: Cholesterol Metabolism Reprogramming in Pancreatic Adenocarcinoma

NCT04862260Phase 1Active, not recruiting

Sponsor
CHU de Québec-Université Laval
Start
Oct 2021
Primary completion
Jan 2025
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of atorvastatin, ezetimibe and evolocumab in pancreatic ductal adenocarcinoma (PDAC), sponsored by CHU de Québec-Université Laval. Primary endpoints: Adverse Events at 2 years and Dose-Limiting Toxicities at 2 years. Started Oct 2021; status: active, not recruiting.

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Drugs

atorvastatinezetimibeevolocumab
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Conditions

pancreatic ductal adenocarcinoma (PDAC)

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