Trial intelligence / Profile preview

TCRT-ESO-A2 in advanced solid tumors

NCT04878484Phase 1Withdrawn

Sponsor
Athenex
Start
Aug 2021
Primary completion
Oct 2022
Modality
Gene Editing, Gene Silencing, TCR-Engineered T Cells
01

Overview

Phase 1, open-label trial of TCRT-ESO-A2 in head and neck cancer (HNC), hepatocellular carcinoma (HCC), squamous cell carcinoma of the lung (LSCC) and 2 more, sponsored by Athenex. Primary endpoint: Dose Limiting Toxicity at Day 28. Planned start Aug 2021; status: withdrawn.

02

Drugs

TCRT-ESO-A2
03

Conditions

head and neck cancer (HNC)hepatocellular carcinoma (HCC)squamous cell carcinoma of the lung (LSCC)synovial sarcoma (SS)triple-negative breast cancer (TNBC)

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