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Mechanistic Study of AZD3427 in Heart Failure

NCT04890548Phase 1Withdrawn

Sponsor
AstraZeneca
Start
Nov 2021
Primary completion
Aug 2022
Modality
Fc-Fusion Proteins
01

Overview

Phase 1, open-label trial of AZD3427 in heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) (2 cohorts), sponsored by AstraZeneca. Primary endpoint: Maximum change from baseline in absolute forearm blood flow at Day 1. Planned start Nov 2021; status: withdrawn.

02

Drugs

AZD3427
03

Conditions

heart failure with preserved ejection fraction (HFpEF)heart failure with reduced ejection fraction (HFrEF)

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