Trial intelligence / Profile preview

Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer

NCT04918186Phase 2Recruiting

Sponsor
Canadian Cancer Trials Group
Start
May 2022
Primary completion
Dec 2026
Modality
Recombinant Proteins and Enzymes, Antibody-Drug Conjugates (ADCs), Engineered Antibody Formats
Countries
2
01

Overview

Phase 2, open-label trial of durvalumab, mecbotamab vedotin, ozuriftamab vedotin, ENB-003 and toripalimab in High-Grade Serous Ovarian Carcinoma (HGSOC) (3 arms), sponsored by Canadian Cancer Trials Group. Primary endpoint: Objective Response Rate at 36 months. Started May 2022; status: recruiting.

02

Drugs

durvalumabmecbotamab vedotinozuriftamab vedotinENB-003toripalimab
03

Conditions

High-Grade Serous Ovarian Carcinoma (HGSOC)

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