Trial intelligence / Profile preview

OptiMATe: De-escalated Induction Treatment in Newly Diagnosed PCNSL

NCT04931368Phase 3Active, not recruiting

Sponsor
Klinikum Stuttgart
Start
Jun 2021
Primary completion
Jun 2028
Modality
Monoclonal Antibodies, Orthosteric Ligands
Countries
1
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Overview

Phase 3, randomised, open-label trial of rituximab, methotrexate, cytarabine and thiotepa in primary central nervous system lymphoma (PCNSL) (2 arms), sponsored by Klinikum Stuttgart. Primary endpoint: Event-free survival. Started Jun 2021; status: active, not recruiting.

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Drugs

rituximabmethotrexatecytarabinethiotepa
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Conditions

primary central nervous system lymphoma (PCNSL)

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