Trial intelligence / Profile preview

PET/CT with ⁸⁹Zr Df-IAB22M2C in Metastatic Melanoma

NCT04955262Phase 1Withdrawn

Sponsor
Nektar Therapeutics
Start
Aug 2019
Primary completion
Jun 2021
Modality
Antibody Fragments, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 1, open-label trial of zirconium-89 crefmirlimab berdoxam in melanoma (2 cohorts), sponsored by Nektar Therapeutics. Primary endpoints: Lesion uptake of ⁸⁹Zr-Df-IAB22M2C at 18 months and Correlation of ⁸⁹Zr Df-IAB22M2C lesion uptake with lesion size and ORR at 18 months. Planned start Aug 2019; status: withdrawn.

02

Drugs

zirconium-89 crefmirlimab berdoxam
03

Conditions

melanoma

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