Trial intelligence / Profile preview

Amivantamab and Lazertinib + Chemotherapy in EGFR-Mutated NSCLC After Osimertinib Failure

NCT04988295Phase 3Active, not recruiting

Sponsor
Janssen Pharmaceutical
Start
Nov 2021
Primary completion
Jul 2023
Modality
Fragment-Derived Small Molecules, Bispecific Antibodies, Orthosteric Ligands
Countries
29
01

Overview

Phase 3, randomised, open-label trial of amivantamab and lazertinib in non-small cell lung cancer (NSCLC) (5 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Progression-free Survival and Treatment-emergent Adverse Events and Treatment-emergent Serious Adverse Events. Started Nov 2021; status: active, not recruiting.

02

Drugs

amivantamablazertinib
03

Conditions

non-small cell lung cancer (NSCLC)

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