Trial intelligence / Profile preview

IMC001 (EpCAM CAR-T) in Advanced Digestive System Malignancies

NCT05028933Phase 1Recruiting

Sponsor
Zhejiang University
Start
Sep 2021
Primary completion
Dec 2024
Modality
CAR-T Cells, Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label trial of autologous CAR-T cell injection targeting EpCAM in hepatocellular carcinoma (HCC), colorectal cancer (CRC), gastric cancer (GC) and 1 more (2 arms), sponsored by Zhejiang University. Primary endpoints: Dose Limiting Toxicity at 28 days, Maximum Tolerated Dose at 28 days and 1 more. Started Sep 2021; status: recruiting.

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Drugs

autologous CAR-T cell injection targeting EpCAM
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Conditions

hepatocellular carcinoma (HCC)colorectal cancer (CRC)gastric cancer (GC)pancreatic cancer (PC)

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