Trial intelligence / Profile preview

JNJ-75220795 Single Ascending Dose in Japanese Participants with Fatty Liver

NCT05039710Phase 1Terminated

Sponsor
Janssen Pharmaceutical
Start
Nov 2021
Primary completion
Feb 2023
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of ARO-PNPLA3 in non-alcoholic fatty liver disease (NAFLD) (2 cohorts), sponsored by Janssen Pharmaceutical. Primary endpoints: Number of Participants with Treatment-emergent Signs and Symptoms/Adverse Events (AEs), Number of Participants With Change From Baseline in Vital Signs Abnormalities and 3 more. Started Nov 2021; status: terminated.

02

Drugs

ARO-PNPLA3
03

Conditions

non-alcoholic fatty liver disease (NAFLD)

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