Trial intelligence / Profile preview

CD19 CAR T Cells in Relapsed/Refractory DLBCL

NCT05052528Phase 1Active, not recruiting

Sponsor
University of California, Davis
Start
Sep 2021
Primary completion
May 2027
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label trial of Super CAR-T in diffuse large B-cell lymphoma (DLBCL) (6 arms), sponsored by University of California, Davis. Primary endpoints: Proportion of products successfully manufactured meeting the established release criteria at 15 years, Incidence and severity of adverse events related to lymphodepleting chemotherapy and or CD19 CAR T cells at 2 months and 3 more. Started Sep 2021; status: active, not recruiting.

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Drugs

Super CAR-T
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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