Trial intelligence / Profile preview

Pegcetacoplan in C3 glomerulopathy and IC-MPGN

NCT05067127Phase 3Completed

Sponsor
Apellis Pharmaceuticals
Start
Nov 2021
Primary completion
Jun 2024
Modality
PEGylated Peptides
Countries
19
01

Overview

Phase 3, randomised, double-blind trial in Complement 3 glomerulopathy (C3G) and Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) comparing Pegcetacoplan with Placebo (2 arms). Primary endpoint: Change From Baseline in Log-Transformed Urine Protein-to-Creatinine Ratio at 26 weeks. Started Nov 2021; status: completed.

02

Drugs

pegcetacoplan
03

Conditions

Complement 3 glomerulopathy (C3G)Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)

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