Trial intelligence / Profile preview

Axicabtagene Ciloleucel in R/R HIV-Associated Aggressive B-Cell NHL

NCT05077527Phase 1Recruiting

Sponsor
AIDS Malignancy Consortium
Start
Feb 2025
Primary completion
Jan 2028
Modality
CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of axicabtagene ciloleucel in aggressive B cell non-Hodgkin lymphoma, sponsored by AIDS Malignancy Consortium. Primary endpoints: Safety of chimeric antigen receptor (CAR) T-cell therapy at 2 years and Feasibility of CAR-T Therapy at 2 years. Started Feb 2025; status: recruiting.

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Drugs

axicabtagene ciloleucel
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Conditions

aggressive B cell non-Hodgkin lymphoma

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