Trial intelligence / Profile preview

CAR.70/IL15-transduced CB-NK Cells With Chemotherapy for Relapsed/Refractory Hematological Malignancies

NCT05092451Phase 2Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Nov 2022
Primary completion
Aug 2030
Modality
Lymphokine-Activated Killer Cells, CAR-NK Cells
Countries
1
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Overview

Phase 2, open-label, single-arm trial of CAR.70/IL15-transduced CB-NK cells in B cell lymphoma, myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) and 8 more, sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Treatment-Related Adverse Events at 1 year, Complete or Partial Response at 30 days and 1 more. Started Nov 2022; status: recruiting.

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Drugs

CAR.70/IL15-transduced CB-NK cells
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Conditions

B cell lymphomamyelodysplastic syndrome (MDS)acute myeloid leukemia (AML)multiple myeloma (MM)plasma cell leukemia (PCL)

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