Trial intelligence / Profile preview

Zilebesiran as add-on therapy in hypertension

NCT05103332Phase 2Completed

Sponsor
Alnylam Pharmaceuticals
Start
Nov 2021
Primary completion
Dec 2023
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
8
01

Overview

Phase 2, randomised, double-blind trial of zilebesiran in hypertension (HTN) (6 arms), sponsored by Alnylam Pharmaceuticals. Primary endpoints: Change from baseline at Month 3 in 24-hour mean systolic blood pressure assessed by ABPM - Indapamide cohort, Change from baseline at Month 3 in 24-hour mean systolic blood pressure assessed by ABPM - Amlodipine cohort and 1 more. Started Nov 2021; status: completed.

02

Drugs

zilebesiran
03

Conditions

hypertension (HTN)

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