Trial intelligence / Profile preview

Pioglitazone for Stress Reactivity and Alcohol Craving

NCT05107765Phase 2Completed

Sponsor
UTHealth Houston
Start
May 2022
Primary completion
Aug 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in alcohol use disorder (AUD) comparing Pioglitazone with Placebo (2 arms). Primary endpoints: Change in Stress-reactivity as Assessed by Heart Rate Change During the Cold Pressor Task at Week 8, Change in Stress-reactivity as Assessed by Change in Systolic Blood Pressure During the Cold Pressor Task at Week 8 and 3 more. Started May 2022; status: completed.

02

Drugs

pioglitazone
03

Conditions

alcohol use disorder (AUD)

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