Trial intelligence / Profile preview

PRT1419 in R/R Myeloid or B-cell Malignancies

NCT05107856Phase 1Terminated

Sponsor
Prelude Therapeutics
Start
Mar 2022
Primary completion
Jan 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of PRT1419 in acute myeloid leukemia (AML), chronic myelomonocytic leukemia (CMML), myelodysplastic syndrome (MDS) and 8 more (3 arms), sponsored by Prelude Therapeutics. Primary endpoints: Dose limiting toxicities at Day 28, Safety and tolerability of PRT1419 at 3 years and 1 more. Started Mar 2022; status: terminated.

02

Drugs

PRT1419
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Conditions

acute myeloid leukemia (AML)chronic myelomonocytic leukemia (CMML)myelodysplastic syndrome (MDS)Myelodysplastic/myeloproliferative neoplasm overlap syndrome (MDS/MPN)chronic lymphocytic leukemia (CLL)

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