Trial intelligence / Profile preview

Zibotentan PK in Hepatic and Renal Impairment

NCT05112419Phase 1Completed

Sponsor
AstraZeneca
Start
Nov 2021
Primary completion
Dec 2021
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of zibotentan in chronic kidney disease (CKD) (2 arms), sponsored by AstraZeneca. Primary endpoints: Area under plasma concentration-time curve from time zero to infinity, Area under the plasma concentration-curve from time zero to time of last quantifiable concentration and 1 more. Started Nov 2021; status: completed.

02

Drugs

zibotentan
03

Conditions

chronic kidney disease (CKD)

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