Trial intelligence / Profile preview

BTX-1188 in Advanced Malignancies

NCT05144334Phase 1Terminated

Sponsor
Biotheryx
Start
Jan 2022
Primary completion
Sep 2023
Modality
Bivalent/Multivalent Binders, PROTACs (E3 ligase recruitment)
Countries
1
01

Overview

Phase 1, open-label trial of sontigidomide in acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL) and solid tumor (7 cohorts), sponsored by Biotheryx. Primary endpoints: Incidence of Treatment-Emergent Adverse Events and Recommended Phase 2 Dose at 28 days. Started Jan 2022; status: terminated.

02

Drugs

sontigidomide
03

Conditions

acute myeloid leukemia (AML)non-Hodgkin lymphoma (NHL)solid tumor

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