Trial intelligence / Profile preview

Mosunetuzumab + Polatuzumab Vedotin vs R-GemOx in R/R Aggressive B-Cell Non-Hodgkin's Lymphoma

NCT05171647Phase 3Active, not recruiting

Sponsor
Roche
Start
Apr 2022
Primary completion
Feb 2025
Modality
Bispecific Antibodies, Antibody-Drug Conjugates (ADCs), Monoclonal Antibodies
Countries
13
01

Overview

Phase 3, randomised, open-label trial of mosunetuzumab and polatuzumab vedotin in non-Hodgkin lymphoma (NHL) (2 arms), sponsored by Roche. Primary endpoints: Objective Response Rate as Determined by the Independent Review Facility in Interim Analysis Population at 23.8 months and Progression-free Survival as Determined by the IRF at 32 months. Started Apr 2022; status: active, not recruiting.

02

Drugs

mosunetuzumabpolatuzumab vedotin
03

Conditions

non-Hodgkin lymphoma (NHL)

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