Trial intelligence / Profile preview

PRIMER-1: Perioperative Pembrolizumab and Lenvatinib in HCC

NCT05185739Phase 2Recruiting

Sponsor
University College London
Start
Aug 2022
Primary completion
Jul 2028
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in hepatocellular carcinoma (HCC) comparing Pembrolizumab, Lenvatinib and Pembrolizumab + Lenvatinib (3 arms). Primary endpoint: Major pathological response rate at 4 months. Started Aug 2022; status: recruiting.

02

Drugs

pembrolizumablenvatinib
03

Conditions

hepatocellular carcinoma (HCC)

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