Trial intelligence / Profile preview

ALN-APP in Early-onset Alzheimer's Disease

NCT05231785Phase 1Recruiting

Sponsor
Alnylam Pharmaceuticals
Start
Feb 2022
Primary completion
Jan 2029
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
4
01

Overview

Phase 1, randomised, double-blind trial of mivelsiran in early-onset Alzheimer's disease (EOAD) (3 arms), sponsored by Alnylam Pharmaceuticals. Primary endpoint: Frequency of Adverse Events at 42 months. Started Feb 2022; status: recruiting.

02

Drugs

mivelsiran
03

Conditions

early-onset Alzheimer's disease (EOAD)

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