Trial intelligence / Profile preview

EV-ECLIPSE: Enfortumab Vedotin + Pembrolizumab in Urothelial Carcinoma Prior to Surgery

NCT05239624Phase 2Active, not recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
Jun 2022
Primary completion
Jun 2027
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes, Antibody-Drug Conjugates (ADCs)
Countries
1
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Overview

Phase 2, open-label, single-arm trial of enfortumab vedotin and pembrolizumab in urothelial carcinoma (UC), sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Pathologic Complete Response Rate at 2 years. Started Jun 2022; status: active, not recruiting.

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Drugs

enfortumab vedotinpembrolizumab
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Conditions

urothelial carcinoma (UC)

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