Trial intelligence / Profile preview

CD7 CAR-T in Refractory Autoimmune Diseases

NCT05239702Phase 1Unknown

Sponsor
Zhejiang University
Start
Feb 2022
Primary completion
Dec 2024
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label trial of CD7-CART in Crohn's disease, ulcerative colitis (UC), dermatomyositis (DM) and 2 more (5 arms), sponsored by Zhejiang University. Primary endpoints: Dose-limiting toxicity at 28 days and Incidence of treatment-emergent adverse events at 2 years. Status: unknown.

02

Drugs

CD7-CART
03

Conditions

Crohn's diseaseulcerative colitis (UC)dermatomyositis (DM)adult-onset Still's disease (AOSD)rheumatoid arthritis (RA)

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