Trial intelligence / Profile preview

CD4^LVFOXP3 in IPEX Syndrome

NCT05241444Phase 1Active, not recruiting

Start
Mar 2022
Primary completion
Dec 2026
Modality
Gene Editing, Gene Silencing, Cell Therapies
Countries
1
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Overview

Phase 1, open-label trial of CD4^LVFOXP3 in immune dysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX) (2 cohorts). Primary endpoints: Target cell number for dose manufacturing at Day 0 and Maximum Tolerated Dose. Started Mar 2022; status: active, not recruiting.

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Drugs

CD4^LVFOXP3
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Conditions

immune dysregulation polyendocrinopathy enteropathy X-linked syndrome (IPEX)

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