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Effect of Colchicine on Aortic Valve Stenosis Progression (COPAS-Pilot)
NCT05253794Phase 3Completed
- Sponsor
- University of Ottawa Heart Institute
- Start
- Jul 2022
- Primary completion
- Jul 2024
- Modality
- Nucleic Acid-Directed Small Molecules, Classical Binding Small Molecules, Metabolically Activated Prodrugs
- Countries
- 1
01
Overview
Phase 3, randomised, double-blind trial in aortic stenosis (AS) comparing Colchicine with Placebo (2 arms). Primary endpoint: Change in aortic valve calcification activity (18F-NaF uptake) at 6 months. Started Jul 2022; status: completed.
02
Drugs
colchicine
03
Conditions
aortic stenosis (AS)
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