Trial intelligence / Profile preview

Safety and Efficacy of LYL797 in ROR1+ Solid Tumors

NCT05274451Phase 1Terminated

Sponsor
Lyell Immunopharma
Start
Mar 2022
Primary completion
Nov 2024
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of LYL797 in triple-negative breast cancer (TNBC), non-small cell lung cancer (NSCLC), ovarian cancer and 1 more, sponsored by Lyell Immunopharma. Primary endpoints: Incidence of Dose-Limiting Toxicities up to 28 days, Incidence of Treatment-Emergent Adverse Events up to 2 years and 2 more. Started Mar 2022; status: terminated.

02

Drugs

LYL797
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Conditions

triple-negative breast cancer (TNBC)non-small cell lung cancer (NSCLC)ovarian cancerendometrial cancer (EC)

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