Trial intelligence / Profile preview

Gefurulimab PK Study in Proteinuric Kidney Disease

NCT05314231Phase 1Completed

Sponsor
Alexion Pharmaceuticals
Start
Jun 2022
Primary completion
May 2023
Modality
Bispecific Antibodies, Nanobodies (VHH), Monoclonal Antibodies
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of gefurulimab in lupus nephritis (LN), IgA nephropathy (IgAN), primary membranous nephropathy (PMN) and 6 more, sponsored by Alexion Pharmaceuticals. Primary endpoint: Serum Concentration of ALXN1720 at Day 57. Started Jun 2022; status: completed.

02

Drugs

gefurulimab
03

Conditions

lupus nephritis (LN)IgA nephropathy (IgAN)primary membranous nephropathy (PMN)focal segmental glomerulosclerosis (FSGS)diabetic nephropathy (DN)

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