Trial intelligence / Profile preview

AMG 794 in Claudin 6-positive solid tumors

NCT05317078Phase 1Terminated

Sponsor
Amgen
Start
Feb 2023
Primary completion
Dec 2023
Modality
Bispecific Antibodies
Countries
3
01

Overview

Phase 1, open-label trial of AMG 794 in non-small cell lung cancer (NSCLC), epithelial ovarian cancer (EOC), testicular germ cell cancer (TGCC) and 2 more (2 cohorts), sponsored by Amgen. Primary endpoints: Dose Limiting Toxicity at 28 days, Treatment-emergent Adverse Event at 2 years and 1 more. Started Feb 2023; status: terminated.

02

Drugs

AMG 794
03

Conditions

non-small cell lung cancer (NSCLC)epithelial ovarian cancer (EOC)testicular germ cell cancer (TGCC)endometrial cancer (EC)triple-negative breast cancer (TNBC)

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