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Mitoxantrone Liposome Combination Therapy in Advanced Solid Tumors

NCT05344742Phase 1Unknown

Sponsor
CSPC ZhongQi Pharmaceutical Technology
Start
Apr 2022
Primary completion
Mar 2024
Modality
Lipid-based Nanoparticles, CAR-T Cells, Small Molecules
01

Overview

Phase 1, open-label trial of mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells in solid tumor (2 arms), sponsored by CSPC ZhongQi Pharmaceutical Technology. Primary endpoints: Dose Limiting Toxicity at 21 days and Treatment-Emergent Adverse Events. Status: unknown.

02

Drugs

mitoxantrone hydrochloride liposome injection + fludarabine + CD19 CAR-T cells
03

Conditions

solid tumor

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