Trial intelligence / Profile preview

Organoid-Guided vs Empirical Neoadjuvant Therapy in Rectal Cancer

NCT05352165Not yet recruiting

Sponsor
Shanghai Minimally Invasive Surgery Center
Start
Jan 2023
Primary completion
Dec 2024
Modality
Immune Checkpoint Inhibitors, DNA Intercalators/Alkylators, Recombinant Proteins and Enzymes
01

Overview

Randomised, open-label trial of fluorouracil, oxaliplatin, irinotecan and pembrolizumab in rectal cancer (2 arms), sponsored by Shanghai Minimally Invasive Surgery Center. Primary endpoint: Pathologic Complete Response at 3 years. Planned start Jan 2023; status: not yet recruiting.

02

Drugs

fluorouraciloxaliplatinirinotecanpembrolizumab
03

Conditions

rectal cancer

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