Trial intelligence / Profile preview

RH5.2 VLP and R21 Malaria Vaccines in Adults and Infants in the Gambia

NCT05357560Phase 1Completed

Sponsor
University of Oxford
Start
Jul 2023
Primary completion
Dec 2025
Modality
Recombinant Protein Vaccines
Countries
1
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Overview

Phase 1, open-label trial of RH5.2 virus-like particle and R21/Matrix-M in malaria (9 arms), sponsored by University of Oxford. Primary endpoints: Occurrence of solicited local reactogenicity signs and symptoms, Occurrence of solicited systemic reactogenicity signs and symptoms and 3 more. Started Jul 2023; status: completed.

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Drugs

RH5.2 virus-like particleR21/Matrix-M
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Conditions

malaria

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