Trial intelligence / Profile preview

Imetelstat in Combination With Ruxolitinib in Patients With Myelofibrosis

NCT05371964Phase 1Active, not recruiting

Sponsor
Geron Corporation
Start
May 2022
Primary completion
Feb 2027
Modality
Antisense DNA, Small Interfering RNA (siRNA), MicroRNA (miRNA)
Countries
1
01

Overview

Phase 1, open-label trial of imetelstat in myelofibrosis (MF) (2 arms), sponsored by Geron Corporation. Primary endpoints: Dose-limiting Toxicity at 28 days, Treatment-emergent Adverse Event up to 5 years and 1 more. Started May 2022; status: active, not recruiting.

02

Drugs

imetelstat
03

Conditions

myelofibrosis (MF)

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