Trial intelligence / Profile preview

Neratinib and Trastuzumab Deruxtecan in HER2-Altered Solid Tumors

NCT05372614Phase 1Recruiting

Sponsor
National Cancer Institute
Start
Oct 2022
Primary completion
Jul 2028
Modality
Fragment-Derived Small Molecules, Monoclonal Antibodies, Allosteric Modulators
Countries
1
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Overview

Phase 1, open-label, single-arm trial of neratinib and trastuzumab deruxtecan in solid tumor and pancreatic adenocarcinoma (PDAC), sponsored by National Cancer Institute. Primary endpoints: Dose Limiting Toxicities, Treatment-Emergent Adverse Events and 1 more. Started Oct 2022; status: recruiting.

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Drugs

neratinibtrastuzumab deruxtecan
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Conditions

solid tumorpancreatic adenocarcinoma (PDAC)

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