Trial intelligence / Profile preview

TMLI and Alemtuzumab as Conditioning Regimen in Sickle Cell Disease

NCT05384756Phase 1Active, not recruiting

Sponsor
City of Hope
Start
Jul 2022
Primary completion
Dec 2026
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of alemtuzumab in sickle cell disease (SCD), sponsored by City of Hope. Primary endpoints: Incidence of adverse events at 100 days and Feasibility at 2 years. Started Jul 2022; status: active, not recruiting.

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Drugs

alemtuzumab
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Conditions

sickle cell disease (SCD)

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