Trial intelligence / Profile preview

ADCT-601 Monotherapy and Combination in Advanced Solid Tumors

NCT05389462Phase 1Terminated

Sponsor
ADC Therapeutics
Start
Jul 2022
Primary completion
Apr 2025
Modality
Monoclonal Antibodies, Antibody-Drug Conjugates (ADCs), Small Molecules
Countries
4
01

Overview

Phase 1, open-label trial of mipasetamab uzoptirine in soft tissue sarcoma (STS), bone sarcoma, non-small cell lung cancer (NSCLC) and 2 more (4 arms), sponsored by ADC Therapeutics. Primary endpoints: Safety and Tolerability as Assessed by Number of Participants with Adverse Events, Number of Participants who Experience a Dose Limiting Toxicity and 2 more. Started Jul 2022; status: terminated.

02

Drugs

mipasetamab uzoptirine
03

Conditions

soft tissue sarcoma (STS)bone sarcomanon-small cell lung cancer (NSCLC)pancreatic adenocarcinoma (PDAC)solid tumor

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