Trial intelligence / Profile preview

Entrectinib in Combination With ASTX727 in Relapsed/Refractory TP53 Mutated AML

NCT05396859Phase 1Active, not recruiting

Sponsor
OHSU Knight Cancer Institute
Start
Oct 2022
Primary completion
Jun 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of entrectinib in acute myeloid leukemia (AML), sponsored by OHSU Knight Cancer Institute. Primary endpoint: Incidence of dose limiting toxicities at 28 days. Started Oct 2022; status: active, not recruiting.

02

Drugs

entrectinib
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Conditions

acute myeloid leukemia (AML)

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