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TvT CAR7: Base Edited CAR7 T Cells in T-Cell Leukaemia
NCT05397184Phase 1Unknown
- Sponsor
- Great Ormond Street Hospital
- Start
- Apr 2022
- Primary completion
- Apr 2024
- Modality
- Gene Silencing, CRISPR-Cas9, CAR-T Cells
- Countries
- 1
01
Overview
Phase 1, open-label, single-arm trial of BE CAR-7 in t-cell acute lymphoblastic leukemia (T-ALL), sponsored by Great Ormond Street Hospital. Primary endpoint: Frequency and description of adverse events after BE-CAR7 infusion at 1 year. Status: unknown.
02
Drugs
BE CAR-7
03
Conditions
t-cell acute lymphoblastic leukemia (T-ALL)
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