Trial intelligence / Profile preview

CAR-NK-CD19 Cells in Relapsed/Refractory B-cell Malignancies

NCT05410041Phase 1Withdrawn

Sponsor
Beijing Boren Hospital
Start
May 2022
Primary completion
Jul 2025
Modality
Gene Editing, Gene Silencing, Lymphokine-Activated Killer Cells
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of CD19 CAR NK cells in acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL), sponsored by Beijing Boren Hospital. Primary endpoints: Safety of CAR NK-CD19 Cell at 3 months and Overall Response Rate at 3 months. Planned start May 2022; status: withdrawn.

02

Drugs

CD19 CAR NK cells
03

Conditions

acute lymphoblastic leukemia (ALL)chronic lymphocytic leukemia (CLL)non-Hodgkin lymphoma (NHL)

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