Trial intelligence / Profile preview

Mosunetuzumab Consolidation Therapy After Autologous Stem Cell Transplantation in Patients With Relapsed/Refractory Aggressive B Cell Lymphoma

NCT05412290Phase 1Active, not recruiting

Sponsor
Washington University School of Medicine
Start
Dec 2022
Primary completion
Sep 2026
Modality
Bispecific Antibodies, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of mosunetuzumab in B cell lymphoma, diffuse large B-cell lymphoma (DLBCL), high grade B-cell lymphoma (HGBCL) and 2 more, sponsored by Washington University School of Medicine. Primary endpoints: Frequencies and grades of treatment-emergent adverse events at 7 months, Rate of treatment discontinuation due to treatment-emergent adverse events at 7 months and 1 more. Started Dec 2022; status: active, not recruiting.

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Drugs

mosunetuzumab
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Conditions

B cell lymphomadiffuse large B-cell lymphoma (DLBCL)high grade B-cell lymphoma (HGBCL)transformed lymphomafollicular lymphoma (FL)

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