Trial intelligence / Profile preview

mRNA-1644 (eOD-GT8 60mer) in HIV-uninfected adults

NCT05414786Phase 1Unknown

Sponsor
International AIDS Vaccine Initiative
Start
May 2022
Primary completion
Jun 2023
Modality
Vaccines & Immunotherapeutics, Lipid-based Nanoparticles, mRNA Therapeutics
Countries
2
01

Overview

Phase 1, open-label, single-arm trial of eOD-GT8 60mer mRNA vaccine in human immunodeficiency virus type 1 infection (HIV-1), sponsored by International AIDS Vaccine Initiative. Primary endpoints: Safety and tolerability of eOD-GT8 60mer mRNA Vaccine at 16 months and VRC01-class IgG B-cells at 16 months. Status: unknown.

02

Drugs

eOD-GT8 60mer mRNA vaccine
03

Conditions

human immunodeficiency virus type 1 infection (HIV-1)

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