Trial intelligence / Profile preview

Safety and PK of ALXN2080 in Healthy Participants

NCT05428696Phase 1Completed

Sponsor
Alexion Pharmaceuticals
Start
Sep 2022
Primary completion
Apr 2023
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of Zoracopan in paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS) and Complement 3 glomerulopathy (C3G) (10 cohorts), sponsored by Alexion Pharmaceuticals. Primary endpoints: Number of Participants Reporting Treatment-Emergent Adverse Events and Number of Participants Reporting Serious Adverse Events. Started Sep 2022; status: completed.

02

Drugs

Zoracopan
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)atypical hemolytic uremic syndrome (aHUS)Complement 3 glomerulopathy (C3G)

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