Trial intelligence / Profile preview

CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Post-autoHSCT in B-NHL

NCT05432635Phase 1Recruiting

Sponsor
City of Hope
Start
Aug 2023
Primary completion
Mar 2028
Modality
Vaccines & Immunotherapeutics, Viral Vectors, CAR-T Cells
Countries
1
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Overview

Phase 1, open-label, single-arm trial of anti-CD19-CAR CMV-specific T-lymphocytes and Triplex in B-cell non-Hodgkin lymphoma, sponsored by City of Hope. Primary endpoint: Incidence of adverse events up to 15 years. Started Aug 2023; status: recruiting.

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Drugs

anti-CD19-CAR CMV-specific T-lymphocytesTriplex
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Conditions

B-cell non-Hodgkin lymphoma

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