Trial intelligence / Profile preview

NEOTOMA: Perioperative Durvalumab + Tremelimumab in Resectable HCC

NCT05440864Phase 2Recruiting

Sponsor
University Health Network
Start
Oct 2023
Primary completion
Nov 2025
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
3
01

Overview

Phase 2, open-label, single-arm trial of tremelimumab and durvalumab in hepatocellular carcinoma (HCC), sponsored by University Health Network. Primary endpoint: Number of greater than grade 3 adverse events (AEs) or immune related adverse events that leads to treatment cessation at 4 years. Started Oct 2023; status: recruiting.

02

Drugs

tremelimumabdurvalumab
03

Conditions

hepatocellular carcinoma (HCC)

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