Trial intelligence / Profile preview

Navitoclax, Venetoclax, and Decitabine for High-risk Myeloid Malignancies

NCT05455294Phase 1Active, not recruiting

Start
Jul 2022
Primary completion
Apr 2024
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of navitoclax in Myeloid malignancy, acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and 2 more (5 arms). Primary endpoints: Recommended Phase 2 Dose at 28 days and Dose Limiting Toxicity at 28 days. Started Jul 2022; status: active, not recruiting.

02

Drugs

navitoclax
03

Conditions

Myeloid malignancyacute myeloid leukemia (AML)myelodysplastic syndrome (MDS)myelofibrosis (MF)Myeloproliferative Neoplasm (MPN)

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