Trial intelligence / Profile preview

IMC002 in CLDN18.2-positive advanced solid tumors

NCT05472857Phase 1Recruiting

Sponsor
Immunofoco
Start
Aug 2022
Primary completion
Dec 2024
Modality
Prophylactic Vaccines, Therapeutic Vaccines, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of claudin 18.2 CAR-T in gastric cancer (GC), pancreatic cancer (PC), ovarian carcinoma and 1 more, sponsored by Immunofoco. Primary endpoints: Incidence of Treatment Related Adverse Events at 12 months and Maximum Tolerated Dose at 28 days. Started Aug 2022; status: recruiting.

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Drugs

claudin 18.2 CAR-T
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Conditions

gastric cancer (GC)pancreatic cancer (PC)ovarian carcinomagastroesophageal junction adenocarcinoma

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