Trial intelligence / Profile preview

Bleximenib + Chemo in Pediatric/Young Adult Acute Leukemias

NCT05521087Phase 1Withdrawn

Sponsor
Janssen Pharmaceutical
Start
Dec 2025
Primary completion
Sep 2026
Modality
Small Molecules
01

Overview

Phase 1, open-label trial of bleximenib in acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL) and acute leukemia of ambiguous lineage (ALAL), sponsored by Janssen Pharmaceutical. Primary endpoints: Number of Participants with Adverse Events and Number of Participants with Dose-Limiting Toxicity. Planned start Dec 2025; status: withdrawn.

02

Drugs

bleximenib
03

Conditions

acute myeloid leukemia (AML)acute lymphoblastic leukemia (ALL)acute leukemia of ambiguous lineage (ALAL)

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