Trial intelligence / Profile preview

Relative Bioavailability of VX-121/TEZ/D-IVA FDC in Healthy Adults

NCT05535959Phase 1Completed

Sponsor
Vertex Pharmaceuticals
Start
Sep 2022
Primary completion
Nov 2022
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, randomised, open-label trial of vanzacaftor, tezacaftor and deutivacaftor in cystic fibrosis (CF) (2 arms), sponsored by Vertex Pharmaceuticals. Primary endpoints: Maximum Observed Plasma Concentration and Area Under the Concentration Versus Time Curve. Started Sep 2022; status: completed.

02

Drugs

vanzacaftortezacaftordeutivacaftor
03

Conditions

cystic fibrosis (CF)

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